I don't think I've ever seen a true left-handed handgun (other than the bolt-action .22LR pistol I have that has the bolt on the right side). I've seen plenty that are very ambidextrous though.
Charter led the way in developing the first truly left-handed revolver. The .38 Special Southpaw is identical to the Undercover Lite, but completely reverse-engineered. The cylinder releases and opens to the right side for your lefty convenience. The Southpaw is also available in a Pink Lady finish.
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